妊娠中麻薬使用による奇形出産

症例対照報告17449例中2.6%、対照 6701例中 2.0%

有意なのはconoventricular(junctional)VSD(OR, 2.7; 95% CI, 1.1–6.3)、心房中隔欠損(OR, 2.0; 95% CI, 1.2–3.6)、左室低形成(OR, 2.4; 95% CI, 1.4–4.1)、二分脊椎(OR, 2.0; 95% CI, 1.3–3.2)、胃壁破裂(OR, 1.8; 95% CI, 1.1–2.9)

Maternal treatment with opioid analgesics and risk for birth defects
American Journal of Obstetrics and Gynecology. DOI: 10.1016/j.ajog.2010.12.039 24 February 2011



参照:Opioid Painkillers Linked to Birth Defects
Study Shows Codeine and Other Painkillers May Be Risky During Pregnancy
http://www.webmd.com/baby/news/20110302/opioid-painkillers-linked-to-birth-defects

by internalmedicine | 2011-03-03 11:24 | 環境問題  

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