咳嗽とQOL

結論として、”呼吸器疾患の種類にかかわらず、疾患横断的に、咳は健康状態と逆相関を示す。
LCQとCQLQともに咳嗽の程度に関して追加情報をもたらす点で 重要
である”ということ

ただ、属性に関して疾患毎の違いがありそうである・・・慢性咳嗽の心理的側面、


Impact of Cough Across Different Chronic Respiratory Diseases
Comparison of Two Cough-Specific Health-Related Quality of Life Questionnaires
(Chest. 2008; 134:295-302)
2つの咳特異的HRQoLのスコアの横断的比較

・Leicester Cough Questionnaire (LCQ)
・Cough Quality of Life Questionnaire (CQLQ)


+一般的HRQoL測定である、EuroQolも施行

147名(慢性咳嗽 83名、COPD 18名、喘息 20名、気管支拡張 26名)


【結果】2群間でLCQとCOLQの有意な差なし(p = 0.24 and p = 0.26, respectively)

アンケートの属性毎の検討解析は4群間の心理的問題・機能的障害の違いが見いだされた (p = 0.01 and p = 0.05, respectively)

COLQスコアは、慢性咳嗽者において、心理的問題が気管支拡張患者より多く (p = 0.03) 、COPD患者より機能障害が少ない(p=0.04)ことを示唆する。

4疾患群全てで、一般健康状態に有意差がある(p = 0.04)。


CQLQとLCQの有意な逆相関が見られた(慢性咳嗽 r = – 0.56, p < 0.001; COPD r = – 0.49, p = 0.04; 喘息 r = – 0.94, p < 0.001; 気管支拡張 r = – 0.88, p < 0.001)。

EuroQol VASにおける有意な相関がCOPD患者では認められる (r = 0.639, p = 0.004) が、咳アンケートスコアとFEV1の関連は認められない




Development of a symptom specific health status measure for patients with chronic cough: Leicester Cough Questionnaire (LCQ) Thorax 2003;58:339-343(full free pdf
a0007242_8414335.jpg



CSQoL
Evaluation of a Cough-Specific Quality-of-Life Questionnaire
(Chest. 2002;121:1123-1131.)
1 Family and or close friends can’t tolerate it anymore.
2 I have experienced prolonged absences from important activities such as work, school, or volunteer services.
3 I have been completely prevented from engaging in important activities such as work, school, or volunteer services.
4 I have lost my appetite.
5 I am sick to my stomach and vomit.
6 I cough and it makes me retch (dry heaves).
7 I have a fear that I might have AIDS or tuberculosis.
8 I have headaches.
9 I am concerned that I have cancer.
10 I am dizzy.
11 I wet my pants.
12 I soil my pants.
13 I sweat.
14 I am hoarse.
15 It hurts when I breathe.
16 I broke a rib.
17 I cannot sleep at night.
18 I have difficulty speaking on the phone.
19 I can no longer sing, for instance, in church.
20 I have stopped going to social activities such as movies, plays, and town meetings.
21 I have had to change my lifestyle.
22 I ache all over.
23 I am exhausted.
24 I am embarrassed.
25 I am upset by people thinking that I have something wrong with me.
26 I want to be reassured that I do not have anything seriously the matter with me.
27 I am self-conscious.
28 I am concerned that I have something seriously the matter with me.


日本版EuroQolについて:<pdf>

by internalmedicine | 2008-08-09 08:41 | 呼吸器系  

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