薬剤副作用推測モデル：predictive pharmacosafety networks (PPNs)

predictive pharmacosafety networks (PPNs)

８０９薬剤からの８５２の副作用を補足する薬剤安全性データベースからのスナップショットを用いて未認識の薬剤・ＡＤＥｓ検知デザインツール


AUROC (area under the receiver operating characteristic curve) statistic of 0.87, with a sensitivity of 0.42 given a specificity of 0.95.

COMPUTATIONAL PHARMACOLOGY
Predicting Adverse Drug Events Using Pharmacological Network Models
Sci Transl Med 21 December 2011:Vol. 3, Issue 114, p. 114ra127


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