慢性呼吸不全COPD患者のHRQOL測定法の相違

Health-related quality of life in COPD patients with chronic respiratory failure
Duiverman et al. Eur Respir J.2008; 0: 09031936.00163607v1

health-related quality of life (HRQoL) 評価

・Maugeri Respiratory Failure (MRF-28)
・Severe Respiratory Insufficiency (SRI) Questionnaire
・Chronic Respiratory Questionnaire (CRQ)

MRF-28はADL重視、SRI、CRQは不安・うつ重視型

MRF-28：Analysis of factors that characterize health impairment in patients
with chronic respiratory failure
Eur Respir J 1999; 13: 1293±1300（pdf）"Maugeri Foundation" Respiratory Failure item set (MRF-28), as subdivided by principal components analysis

Factor 1-daily activities

・Washing myself (face, neck, etc.) usually makes me feel
breathless
・Combing my hair or shaving myself usually makes me feel
breathless
・Getting dressed usually makes me feel breathless
・Because of my lung disease, I am unable to shower as I
would like to
・Because of my lung disease, I cannot put on my socks,
stockings or shoes as I would like to
・Because of my lung disease, I am not able to cook as I
would like to
・Because of my lung disease, I cannot do housework or
light repairs around the house as I would like to
・Because of my lung disease, when I need to, I cannot bend
over as I would like to
・Because of my lung disease, when I need to, I cannot pick
up light things as I would like to
・Because of my lung disease, I cannot play with children as
I would like to
・Because of my lung disease, I cannot talk as much as I
would like to

Factor 2±cognitive function

・I forget names now more than I used to
・I am very absent minded
・When I am talking, I often forget what I wanted to say
・Even when something interests me very much I cannot maintain concentration as long as I would like to

Factor 3±invalidity

・Because of my lung disease, I have become an invalid
・Because of my lung disease, everything seems too much of
an effort
・Because of my lung disease, I go out to see friends or
acquaintances less than usual
・Because of my lung disease, I spend much more time alone
・Because of my lung disease, when I am outside I feel I
need to have someone with me

Items with a correlation coefficient <0.5 with any factor

・I feel tired in the morning
・I feel unrefreshed in the morning
・I feel irritable during the daytime
・I think my respiratory problem is incurable
・Because of my respiratory disease I feel that I am a burden to my family
・Because of my respiratory disease I avoid going shopping
・Standing up makes me breathless
・My respiratory device interferes with my life a lot

SRI原著

Windisch W, Freidel K, Schucher B, Baumann H, Wiebel M, Matthys H, Petermann F: The Severe Respiratory Insufficiency (SRI) Questionnaire: a specific measure of health-related quality of life in patients receiving home mechanical ventilation. J Clin Epidemiol 2003, 56:752-759.