中国漢方システミック・レビュー：癌患者への投与

システミックレビューというと・・・こちらも身構えるが・・・中国漢方全部をまとめてレビューするという乱暴な報告
　↓
A systematic review of the effectiveness of Chinese herbal medication in symptom management and improvement of quality of life in adult cancer patients
Complementary Therapies in Medicine　Volume 17, Issue 2, April 2009, Pages 92-120

システミック・レビューの目的は、癌治療患者と同時使用の中国漢方の有効性を、毒性マネージメントと、QoLや生存率を含め検討すること

４９トライアルが参入クライテリアに合致し、標準的プロセスに従いレビュー
対象　３９９２患者で、副作用の改善、QoLやperformance status改善を示す大多数の研究で、腫瘍退縮や生存率改善の報告もある

臨床的推奨は存在しないが、中国漢方は癌治療に役割を果たすに充分な報告を示す研究の数々がある。しかし、結論を出すのに必要な、方法論的に充分な研究がより多く必要

PubMedだと、”chinese herbal cancer”で、1928件

× "trial"　：(273)
× "randomized”　：(277)
× "survival" ：(69)
× "randomized mortality"　：(26)
× "pollative”　：(277）

・・・これを一つずつ調べても・・・なかなか、これといった論文が見つからない


小柴胡湯が再評価される時が来るのだろうか？・・・副作用の問題だから・・・困難だと思うが・・・

Current strategies for chemoprevention of hepatocellular carcinoma.
Oncology. 2002;62 Suppl 1:24-8.

緩和ケアと漢方
・Complementary therapies in palliative cancer care
Oncology and Radiotherapy Volume 91 Issue 11, Pages 2181 - 2185

・Herbal use among cancer patients during palliative or curative chemotherapy treatment in Norway

Supportive Care International Volume 16, Number 7 0941-4355 2008.7


Dietary supplements in patients with cancer: Risks and key concepts, part 1
Michaud et al. Am J Health Syst Pharm.2007; 64: 369-381



Safety and Efficacy of Herbal Sedatives in Cancer Care
Block et al. Integr Cancer Ther.2004; 3: 128-148

Studies of better-known herbal sedatives, notably valerian and kava, showed moderate evidence for both safety and efficacy for valerian while revealing disturbing toxicity concerns for kava. Milder sedatives or anxiolytics in need of clinical study include German chamomile, lavender, hops, lemon balm, and passionflower; St. John’s wort may have anxiolytic effects with relevance to sleep. Herb-drug interactions are a possibility for some of these species, including St. John’s wort. Although sufficient evidence exists to recommend some of these agents for short-term relief of mild insomnia, long-term trials and observational studies are needed to establish the safety of prolonged use as well as overall efficacy in the context of cancer treatment and management.

Complementary and Alternative Medicine: The Role of the Cancer Center
Journal of Clinical Oncology, Vol 19, No 18S (September 15 Supplement), 2001: 55s-60s