メトホルミンの癌抑制効果
2009年 11月 07日
VIENNA — The glucose-lowering drug metformin is increasingly showing an anticancer effect. The data come from studies conducted in both the diabetes and oncology research communities, according to expertswat the annual meeting of the European Association for the Study of Diabetes.
Internal Medicine News Volume 42, Issue 19, Page 22 (1 November 2009)
調べてみると・・・
Dr. Edwin Gale, MD(Department of Diabetic Medicine and head of the Department of Clinical Science at the University of Bristol in the United Kingdom)の発表
2型糖尿病後顧的研究で、イギリスの300のGP記録
インスリン単独治療:1000人年 60
インスリン+メトフォルミン群:1000人年 34
補正後、5.73 vs 3.20
http://www.medscape.com/viewarticle/709790
メトフォルミンと乳がんの関連は話題になっていた。そして、癌の抑制効果の仕組みも・・・
Metformin Is an AMP Kinase–Dependent Growth Inhibitor for Breast Cancer Cells
Cancer Research 66, 10269, November 1, 2006. Published Online First October 23, 2006;
http://jco.ascopubs.org/cgi/reprint/JCO.2009.22.1630v1.pdf
by internalmedicine | 2009-11-07 11:32 | がん